Palpanas
Graviola is Annona muricata which is a species of the genus Annona of the custard
apple tree family, Annonaceae, known mostly for its edible fruit. The
fruit is usually called soursop due to its slightly acidic taste when
ripe. It grows very well in the soils of Bardez but there is negligible production. We are thankful for Portuguese to bring Graviola species in Goa. It is very hard to see these fruits in markets of Goa and those who bring it charges around 100-200 Rupees per fruit. Government should promote cultivation of this fruit. The day is not far when Indian Government will soon realize its tremendous pharmaceutical potential for mainly to cure Cancer. Oil extracted from its seeds offers many properties which includes antibacterial,
astringent, hypotensive and sedative to name a few. Their traditional
uses are to treat asthma, chills, fever, flue, high blood pressure,
insomnia, nervousness, rheumatism and skin diseases. Use it in creams, lotions and ointments to relieve itching of dry skin
and eczema and psoriasis symptoms. The seed has high amount of magnesium
and potassium with respect to the fruit pulp.
In 2008
the NCI supported the Purdue research, which confirmed that
extracts from Graviola leaves killed cancer cells among six human-cell lines
and were especially effective against prostate and pancreatic cancers. Another
study showed their effect against lung cancer.
Yang et. al., 2014 showed Synergistic interactions among flavonoids and acetogenins in Graviola (Annona muricata) leaves which confered protection against prostate cancer.
George et. al., 2015 showed DNA protective and antioxidant efficacy of Annona muricata leaf extracts. In 2014, also, Asare et. al., showed antiproliferative activity of aqueous leaf extract of Annona muricata on the Prostate, BPH-1 Cells, and some target genes.
Minari & Okeke 2014, showed chemopreventive effect of Annona muricata on DMBA-induced cell proliferation in the breast tissues of female albino mice.
There is only one mechanishm evaluated for the anticancer activity by Moghadamtousi et. al., 2014, which stated that Annona muricata leaves induces apoptosis in lung cancer A549 cells through mitochondrial-mediated pathway and involvement of NF-κB.
Goa government with ICAR should promote cultivation of Graviola in whole Goa. This might give farmers some incentives from Pharmaceutical Industries buying these fruits directly from them.
there
is substantial potential for herb-drug interactions that may reduce the
efficacy of chemotherapeutic agents. - See more at:
http://www.cancernetwork.com/integrative-oncology/graviola-annona-muricata#sthash.2phMk4kQ.dpuf
there
is substantial potential for herb-drug interactions that may reduce the
efficacy of chemotherapeutic agents. - See more at:
http://www.cancernetwork.com/integrative-oncology/graviola-annona-muricata#sthash.2phMk4kQ.dpuf
there
is substantial potential for herb-drug interactions that may reduce the
efficacy of chemotherapeutic agents. - See more at:
http://www.cancernetwork.com/integrative-oncology/graviola-annona-muricata#sthash.2phMk4kQ.dpuf
there
is substantial potential for herb-drug interactions that may reduce the
efficacy of chemotherapeutic agents. - See more at:
http://www.cancernetwork.com/integrative-oncology/graviola-annona-muricata#sthash.2phMk4kQ.dpuf
there
is substantial potential for herb-drug interactions that may reduce the
efficacy of chemotherapeutic agents. - See more at:
http://www.cancernetwork.com/integrative-oncology/graviola-annona-muricata#sthash.2phMk4kQ.dpuf
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